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Meg Ryan has published a heartfelt tribute to the departed filmmaker Rob Reiner, who directed her in the iconic rom-com When Harry Met Sally.

A Devastating Incident

Reiner was discovered deceased alongside his spouse, Michele Singer Reiner, at their residence in LA this past weekend.

“Oh how we will miss this man…” the actress posted on Instagram, alongside a picture of them together. “Thank you, Rob and Michelle [sic], for the way you believe in true love, in fairy tales, and in laughter. We appreciate your faith in human goodness and your deep patriotism.”

Charges Filed

Reiner’s son Nick, 32, faces two counts of first-degree murder and appeared in court today. He’s being detained without the option of bail. Reports indicate that Reiner’s daughter Romy discovered her father deceased.

“I must hold onto hope that their tale doesn't conclude here, that awareness can be heightened from this,” Ryan continued. “I don’t know, but my guess is that they would want that to be hopeful and humane, to be something that brings us all to a greater understanding of one another and to some peace.”

Family Members Issue a Message

Reiner’s surviving children Jake and Romy issued words today. “No words can convey the constant, profound sorrow we feel,” they said. “The horrific and devastating loss of our parents, Rob and Michele Reiner, is something that no one should ever experience. They were more than parents; they were our closest confidants.”

Peers Pay Their Respects

Ryan’s co-star, Billy Crystal, similarly honored Reiner with a statement shared yesterday along with names including Larry David, Martin Short and Albert Brooks.

“No one matched his comic instinct, his dedication to rhythmic dialogue, or his elegant sharpening of drama,” the tribute noted. “For the actors, he loved them. For the writers he made them better. Freedom was his key offering. He listened to ideas and included you in the creative journey. They always felt they were working as a team. To be in his hands as a film-maker was a privilege but that is only part of his legacy.”

A Storied Career

When Harry Met Sally was a critical and commercial success in 1989, grossing more than $93 million worldwide and earning Nora Ephron an Oscar nomination for best original screenplay.

Rob Reiner was introduced to Michele Singer Reiner during the production of When Harry Met Sally. The pair were brought together by Barry Sonnenfeld, a fellow filmmaker and pal.

Reiner’s celebrated filmography also included classics such as Misery, Stand by Me and The Princess Bride. The director and his wife were together in marriage for 36 years.